Smoking-associated gene expression alterations in nasal epithelium reveal immune impairment linked to lung cancer risk
Abstract Background Lung cancer is the leading cause of cancer-related death in the world.In contrast to many other cancers, a direct connection to modifiable lifestyle risk in the form of tobacco smoke has long been established.More than 50% of all smoking-related lung cancers occur in former smokers, 40% of which occur more than 15 years after sm